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Anti-idiotypic antibodies: a clinical future?

โœ Scribed by Brent, L. ;Kilshaw, P. J.

Book ID
109701944
Publisher
Nature Publishing Group
Year
1976
Tongue
English
Weight
245 KB
Volume
262
Category
Article
ISSN
0028-0836

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Disialoganglioside GD2 is widely expressed among neuroblastomas, melanomas, small-cell lung carcinoma, sarcomas and brain tumors. Immunity directed against this antigen may have anti-tumor utility. Since GDz is poorly immunogenic, antiidiotypic antibodies may serve as alternative tumor vaccines. Mon