✦ LIBER ✦

Anti-HER2/neu IgG3–(IL-2) and anti-HER2/neu IgG3–(GM-CSF) promote HER2/neu processing and presentation by dendritic cells: Implications in immunotherapy and vaccination strategies

✍ Scribed by Jay Soriano Dela Cruz; Kamh Ryan Trinh; Hsiao Wen Chen; Antoni Ribas; Sherie L. Morrison; Manuel L. Penichet

Book ID: 116755609
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 591 KB
Volume: 43
Category: Article
ISSN: 0161-5890
DOI: 10.1016/j.molimm.2005.04.007

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Insights into the mechanism of anti-tumo

Insights into the mechanism of anti-tumor immunity in mice vaccinated with the human HER2/neu extracellular domain plus anti-HER2/neu IgG3-(IL-2) or anti-HER2/neu IgG3-(GM-CSF) fusion protein

✍ Jay S. Dela Cruz; Sherie L. Morrison; Manuel L. Penichet 📂 Article 📅 2005 🏛 Elsevier Science 🌐 English ⚖ 458 KB

Coexpression of Flt3 ligand and GM-CSF g

Coexpression of Flt3 ligand and GM-CSF genes modulates immune responses induced by HER2/neu DNA vaccine

✍ Yo, Y-T; Hsu, K-F; Shieh, G-S; Lo, C-W; Chang, C-C; Wu, C-L; Shiau, A-L 📂 Article 📅 2007 🏛 Nature Publishing Group 🌐 English ⚖ 416 KB

HER2/neu gene amplification and protein

HER2/neu gene amplification and protein overexpression in G3 pT2 transitional cell carcinoma of the bladder: a role for anti-HER2 therapy?

✍ Z Latif; A.D Watters; I Dunn; K Grigor; M.A Underwood; J.M.S Bartlett 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 551 KB

Vaccination with dendritic cells pulsed

Vaccination with dendritic cells pulsed with apoptotic tumors in combination with anti-OX40 and anti-4-1BB monoclonal antibodies induces T cell–mediated protective immunity in Her-2/neu transgenic mice

✍ Camilo Cuadros; Ana Lucia Dominguez; Pier-Luigi Lollini; Michael Croft; Robert S 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 854 KB

## Abstract Tumor cells express tumor‐associated antigens (TAAs), which can serve as targets for the immune system. However, the majority of TAAs are overexpressed products of normal cellular genes; as such, self‐tolerance mechanisms have hindered their use for the induction of effective antitumor

Primed And Boosted Anti-Breast Cancer Tu

Primed And Boosted Anti-Breast Cancer Tumor Immunity After Autologous Peripheral Blood Stem Cell Transplant (PBSCT): In Vivo Priming With T Cells Armed With Anti-CD3 X anti-Her2/neu Bispecific Antibody (Her2Bi) Pre PBSCT And Boosting After PBSCT With Activated T Cells (ATC)

✍ L.G. Lum; A. Thakur; Z. Al-Kadhimi; M. Abidi; L. Ayash; F. Cummings; R. Rathore; 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 63 KB

Antitumoral actions of the anti-obesity

Antitumoral actions of the anti-obesity drug orlistat (XenicalTM) in breast cancer cells: blockade of cell cycle progression, promotion of apoptotic cell death and PEA3-mediated transcriptional repression of Her2/neu (erbB-2) oncogene

✍ Menendez, J. A. 📂 Article 📅 2005 🏛 Oxford University Press 🌐 English ⚖ 447 KB