Anti-HCV antibody titers before and after interferon therapy in 43 patients with chronic non A non B hepatitis: Relationship with response to treatment
β Scribed by Luncl, F.; Perrin, M.; Valla, D.; Cadranel, J.F.; echabrolle, A.Devil; Grippon, P.; Huraux, J.M.; Opolon, P.
- Book ID
- 121914110
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 118 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0168-8278
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## Abstract A quantitative polymerase chain reaction (PCR) assay for hepatitis C viral RNA (HCVβRNA) was used to monitor viraemia levels in six patients at multiple time points before, during, and after interferon therapy for chronic nonβA, nonβB hepatitis (NANBH). Prior to therapy, serum HCVβRNA w
In a retrospective study, antibody to hepatitis C virus (anti-HCV antibody) was measured in 80 patients with acute viral hepatitis (type A, 18; type B, 21; type non-A,non-B, 41). Anti-HCV antibody was found in 12 of 20 patients (60%) with non-A,non-B post-transfusion hepatitis (NANB-PTH) and in 9 of
Ten patients with chronic hepatitis C, six of whom had not responded and four of whom had responded in a non-sustained fashion to interferon-alpha treatment alone, were given interferon alpha-2b and ribavirin in combination during 24 weeks. Interferon alpha-2b was given subcutaneously, at a dose of