Anti-granulocyte opsonic activity in sera from patients with systemic lupus erythematosus
β Scribed by A. G. Hadley; M. A. Byron; H. M. Chapel; C. Bunch; A. M. Holburn
- Book ID
- 114711206
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 391 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0007-1048
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## Abstract Activated complement components and immune complexes cause neutrophil (PMN) aggregation in vitro and in vivo, as in dialysisβinduced neutropenia and adult respiratory distress syndrome. To investigate the possible role of PMN aggregation in systemic lupus erythematosus (SLE), we studied
Sera obtained from fifty-five patients with active systemic lupus erythematosus (SLE) and from four patients with mixed connective tissue disease (MCTD) previously shown by immunofluorescence and by double immunodiffusion to possess antinuclear antibodies, were tested for the presence of natural ant