✦ LIBER ✦

Anti-cytoplasmic factors in the sera of patients with systemic lupus erythematosus and certain other diseases

✍ Scribed by Helmuth R. G. Deicher; Halsted R. Holman; Henry G. Kunkel

Publisher: John Wiley and Sons
Year: 1960
Tongue: English
Weight: 995 KB
Volume: 3
Category: Article
ISSN: 0004-3591
DOI: 10.1002/art.1780030102

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Complement fixation reactions were obtained with the use of cytoplasmic cellular constituents and sera from patients with S.L.E. as well as sera from cases of primary biliary cirrhosis and Sjogren's syndrome. These reactions were independent of those involving nuclear components. The serum proteins responsible for the described reactions were shown to be gamma globulins. Evidence was produced that different constituents of microsomes were responsible for the reactions in the different diseases.

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