Anti-CD7 antibody and immunotoxin treatment of human CD7+T-cell leukaemia is significantly less effective in NOD/LtSz-scid mice than in CB.17 scid mice

Therapy of human B-cell lymphoma bearing

Therapy of human B-cell lymphoma bearing scid mice is more effective with anti-CD19-and anti-CD38-saporin immunotoxins used in combination than with either immunotoxin used alone

✍ David J. Flavell; Deborah A. Boehm; Loretta Emery; Armorel Moss; Alan Ramsay; So 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 885 KB

The CD19+ CD38+ human Burkitt's lymphoma cell line Ramos grows aggressively when injected intravenously (i.v.) into severe combined immunodeficient (SCID) mice, killing 100% of animals within a 3 3 4 2 day period with widely disseminated disease. Treatment commencing 7 days after i.v. injection of R