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Anti-CD 20 monoclonal antibody (rituximab) treatment for inflammatory ocular diseases

✍ Scribed by E. Miserocchi; I. Pontikaki; G. Modorati; M. Gattinara; P.L. Meroni; V. Gerloni

Book ID
113482493
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
181 KB
Volume
11
Category
Article
ISSN
1568-9972

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Rituximab is a chimeric anti CD-20 monoclonal antibody containing human IgG1 kappa constant regions, with murine variable regions. The anti-lymphoma effects of Rituximab are probably due to complement and antibody-dependent cell-mediated cytotoxicity, and induction of apoptosis. Phase II trials have