𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Anti-apoptotic strategies of lymphotropic viruses

✍ Scribed by Edgar Meinl; Helmut Fickenscher; Margot Thome; Jürg Tschopp; Bernhard Fleckenstein

Book ID
104298949
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
881 KB
Volume
19
Category
Article
ISSN
0167-5699

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✦ Synopsis

Induction of apoptosis of virus-infected cells is an important host cell defence mechanism. However, some viruses have incorporated genes that encode anti-apoptotic proteins or modulate the expression of cellular regulators of apoptosis. Here, Edgar Meinl and colleagues discuss recent evidence that viral interference with host cell apoptosis leads to enhanced viral replication, and to evasion of cytotoxic T-cell effects.

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