Fatal cardiomyopathy developed in two patients receiving cyclophosphamide in preparation for bone marrow transplantation. Both patients had normal EKGs prior to receiving cyclophosphamide in total doses of 168 mg/kg (case 1) and 144 mgkg (case 2) and subsequently developed loss of voltage and ST-T w
โฆ LIBER โฆ
Anthracycline-induced cardiomyopathy in children: A report of six cases
โ Scribed by Dearth, J. ;Osborn, R. ;Wilson, E. ;Kelly, D. ;Mantle, J. ;Rogers, E. ;Malluh, A. ;Crist, W.
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 513 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0098-1532
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โฆ Synopsis
Although anthracycline antibiotics are viewed our experience with anthracyclines over a 5-year period. Cardiomyopathy developed in 6 of 112 patients (5.3%) treated with anthracyclines and was fatal in 5 of the 6 patients. O u r incidence and mortality rates are among the most useful chemotherapy agents, the risk of producing cardiomyopathy and the absence of a reliable noninvasive technique to predict subclinical cardiomyopathy remain a major problem. We retrospectively re-higher than those previously reported.
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