Anthracycline Antitumor Antibiotic · Nucleic-Acid Interactions : Structural Aspects of the Daunomycin · poly(dA-dT) Complex in Solution

Mutagen–nucleic acid complexes at the po

Mutagen–nucleic acid complexes at the polynucleotide duplex level in solution: Intercalation of proflavine into poly(dA-dT) and the melting transition of the complex

✍ Dinshaw J. Patel 📂 Article 📅 1977 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 763 KB

## Abstract The nmr chemical shifts and line widths of the nucleic acid base and sugar proton resonances and the proflavine ring protons can be monitored through the melting transition of the proflavine + poly(dA‐dT) complex, phosphate/dye (__P__/__D__) ratio = 24 and 8 in 1__M__ salt solution. The