Anterior and posterior neural plates from epiblast are derived by distinct molecular mechanisms

Neural mechanisms underlying peak-dose d

Neural mechanisms underlying peak-dose dyskinesia induced by levodopa and apomorphine are distinct: Evidence from the effects of the alpha2 adrenoceptor antagonist idazoxan

✍ Susan H. Fox; Brian Henry; Micheal P. Hill; David Peggs; Alan R. Crossman; Jonat 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 102 KB

## Abstract Dyskinesia, secondary to dopamine replacement therapy, is the major complication of currently available therapies for Parkinson's disease. Alpha~2~ adrenoceptor antagonists, such as idazoxan, can significantly reduce levodopa‐induced dyskinesia in the 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydr