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Antarafacial hydride transfer in a new chiral NADH model with C2-symmetry

✍ Scribed by Klas Skog; Olof Wennerström


Book ID
104224792
Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
283 KB
Volume
33
Category
Article
ISSN
0040-4039

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✦ Synopsis


A Cz-symmetric macrocyclic NAD+lNADH-model, 1, in which hydride transfer occurs in an antarafacial way, has been prepared. On reduction of methyl benzoylformate with 1, methyl mandelate is formed in 95% ee.


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