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Antagonistic effects of HTLV-1 Tax oncoprotein on BRCA1 expression and function

✍ Scribed by Huleihel, Mahmoud; Shukron, Mital; Gabarin, Azhar; Abukandil, Ammar; Aboud, Mordechai

Book ID
121575623
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
74 KB
Volume
11
Category
Article
ISSN
1742-4690

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## Abstract Adult T‐cell leukemia (ATL) is a highly aggressive mature CD4^+^ T‐cell malignancy that is etiologically associated with human T‐lymphotropic virus Type 1 (HTLV‐1). ATL is characterized by frequent infiltration of lymph nodes, spleen, liver, skin and gut. Previously, we and others have