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Antagonism of the behavioral effects of L-phenylisopropyladenosine (L-PIA) by caffeine and its metabolites

โœ Scribed by Lance Logan; John M. Carney

Book ID
114103271
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
446 KB
Volume
21
Category
Article
ISSN
0091-3057

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Stereoselective behavioral effects of N6
Stereoselective behavioral effects of N6-phenylisopropyl-adenosine and antagonism by caffeine
โœ Steven R. Goldberg; Josรฉ A. Prada; Jonathan L. Katz ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› Springer ๐ŸŒ English โš– 663 KB

Effects of the (-)- and (+)-isomers of N6-(phenylisopropyl)-adenosine (PIA) were studied in rats trained to respond under fixed-interval and fixed-ratio schedules of food reinforcement. Both isomers of PIA decreased response rates; however, the (-)-isomer decreased response rates at doses as low as