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Antagonism of morphine-induced central stimulation in mice by small doses of catecholamine-receptor agonists

✍ Scribed by U. Strömbom; T. H. Svensson

Publisher
Springer
Year
1978
Tongue
English
Weight
582 KB
Volume
42
Category
Article
ISSN
1435-1463

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✍ U. Strömbom; T. H. Svensson; A. Carlsson 📂 Article 📅 1977 🏛 Springer 🌐 English ⚖ 649 KB

Small doses of apomorphine (0.03 -0.25 mg/ kg i.p.) caused a dose-dependent suppression of the ethanol-induced (2.36 g/kg, 15 % v/v, i.p.) locomotor stimulation in mice and higher doses (0.5-2 mg/kg i.p.) caused a delayed suppression. The delay increased with increased doses. Very small doses of clo