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Antagonism of ethanol-induced depressant effects by 4-aminopyridine in the central nervous system of the rat

✍ Scribed by L.C. Sellin; P.S. Laakso

Book ID
118955776
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
538 KB
Volume
26
Category
Article
ISSN
0028-3908

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The action of naloxone (0.5 and 2 mg/kg IP) on the behavioural effects of a low (2 g/kg PO) and a high dose (4 g/kg PO) of ethanol was studied in rats. Ethanol at the low dose increased spontaneous motility, enhancing open-field external ambulations and reducing shuttle-box latency. All these effect