Antagonism of cocaine's pharmacological effects by the stimulant dopaminergic antagonists, (+)-AJ76 and (+)-UH232
โ Scribed by M.F. Piercey; J.T. Lum; W.E. Hoffmann; A. Carlsson; E. Ljung; K. Svensson
- Book ID
- 115803440
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 714 KB
- Volume
- 588
- Category
- Article
- ISSN
- 0006-8993
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The in vivo dopamine (DA) receptor binding and behavioural properties of the recently characterised putative preferential DA autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 were studied in rats with a unilateral 6-OH-DA lesion of the substantia nigra. The main findings were a) that (+)-UH 232 and
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