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Anomalously Coupled Nucleosides, II. Reaction of 3-[N6-(4-Chlorophenyl)-2-methyl-9-adenyl]-2,3-dideoxy-D-threo-pentopyranose with Alcohols and Anilines

✍ Scribed by Andersen, Jesper ;Pedersen, Erik B.


Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
393 KB
Volume
1987
Category
Article
ISSN
0947-3440

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✦ Synopsis


3-

[ N"-(4-C hlorp henyt)-l-met hyl-9-adenyl]-2.3-dideoxy-~-lbreopcntopyranosc (1) has been converted into the alkyl 3-[P-(4clila rop henyl)-2-me thyI-9-adenyl]-2,3-dideoxy-o-rhreo-pento~yraiiosides 2 and into thc N-aryl-3-~N6~4-chlorophenyl)-2-methyl-~)-adc:nyl]-2.3-dideoxy-~-fhreo-pcntopyranosylamines 4. Thc compounds 2 wcre isolated as mixtures of CL and p anorners whcreas pure u momers 3 could be ohiained after prolonged reaction I II11L'S.