✦ LIBER ✦

Anomalous metalation behavior in 1,3-oxazoles. Alkylation of 2-methyl-4-carboxyoxazoles via the cornforth intermediate

✍ Scribed by A.I. Meyers; Jon P. Lawson

Book ID: 104234185
Publisher: Elsevier Science
Year: 1981
Tongue: French
Weight: 185 KB
Volume: 22
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)81853-0

No coin nor oath required. For personal study only.

✦ Synopsis

Metalation of the methyl group in the title compound is accomplished through the open chain Cornforth precursor.

This technique is necessary due to the preferred metalation of the 5-H proton in oxazoles.

📜 SIMILAR VOLUMES

Naphth[1,2-d]oxazole intermediates in th

Naphth[1,2-d]oxazole intermediates in the preparation of 3-hydroxy-4-(1-alkyl-3-methyl-5-hydroxy-4-pyrazolyl)-azo-1-naphthalenesulfonamide dyes

✍ Alan R. Katritzky; Bogumila Rachwal; Stanislaw Rachwal; David Macomber; Terrance 📂 Article 📅 1993 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 419 KB

Nitrosation of methyl 2-cinnamoylamino-3

Nitrosation of methyl 2-cinnamoylamino-3-dimethylaminopropenoates. Alkyl N-cinnamoyloxalic acid hydroxyimidic amides, intermediates in the synthesis of alkyl 5-styryl-1,2,4-oxadiazole-3-carboxylates

✍ Matej Kmetič; Branko Stanovnik 📂 Article 📅 1997 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 252 KB

ChemInform Abstract: Nitrosation of Meth

ChemInform Abstract: Nitrosation of Methyl 2-Cinnamoylamino-3-dimethylaminopropenoates. Alkyl N-Cinnamoyloxalic Acid Hydroxyimidic Amides, Intermediates in the Synthesis of Alkyl 5-Styryl-1,2,4-oxadiazole-3-carboxylates.

✍ M. KMETIC; B. STANOVNIK 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 1 views