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Annotation of androgen dependence to human prostate cancer-associated genes by microarray analysis of mouse prostate

โœ Scribed by Jas Singh; Pachiappan Manickam; Michael Shmoish; Sara Natik; Gareth Denyer; David Handelsman; Da-Wei Gong; Qihan Dong


Book ID
116333841
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
113 KB
Volume
237
Category
Article
ISSN
0304-3835

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## Abstract Three unique variants of the CWR22 human prostate cancer xenograft model (CWR22LD1, LD2, and LD3) with a decrease in dependence on androgens were selected under noncastrate conditions, i.e., by outgrowth after transplantation into male NCR (AT) nu mice without testosterone supplementati