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Annexin V inhibits the 12-O-tetradecanoylphorbol-13-acetate-induced activation of Ras/extracellular signal-regulated kinase (ERK) signaling pathway upstream of Shc in MCF-7 cells

✍ Scribed by Sato, Hirokazu; Ogata, Hideaki; De Luca, Luigi M

Book ID
110063939
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
310 KB
Volume
19
Category
Article
ISSN
0950-9232

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## Abstract Protein kinase C (PKC), a family of serine‐threonine kinases, has been implicated in the regulation of colon tumorigenesis. However, the specific isoform of PKC involved in this process is not clear. In the present study, we found that treatment of the cultured human colon cancer cell l