Pyridines are readily annelated with nitriles of a,b-acetylenic g-hydroxyacids under mild conditions (ambient temperature, no catalyst, no solvent) to give new condensed dihydropyridine systems, 4-cyanomethylidene-1,3-oxazolidine[3,2-a]-1,2-dihydropyridines in 75-83% yields.
✦ LIBER ✦
Annelation of Benzimidazoles with α,β-Acetylenic γ-Hydroxyacid Nitriles and Hydrolytic Rearrangement of the Cycloadducts on Alumina
✍ Scribed by Boris A. Trofimov; Ludmila V. Andriyankova; Anastasiya G. Mal'kina; Kseniya V. Belyaeva; Lina P. Nikitina; Oleg A. Dyachenko; Olga N. Kazheva; Anatolii N. Chekhlov; Gennadii V. Shilov; Andrei V. Afonin; Igor' A. Ushakov; Ludmila V. Baikalova
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 158 KB
- Volume
- 2007
- Category
- Article
- ISSN
- 1434-193X
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