Factors determining the relative stabili
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Michael Shokhen; Amnon Albeck
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Article
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2000
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John Wiley and Sons
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English
โ 257 KB
๐ 1 views
Quantum mechanical ab initio (RHF/6-31ุG\*//RHF/3-21G) calculations were used to simulate the formation of the tetrahedral complex intermediate (TC) in serine protease active site by substrates and transition-state analog inhibitors. The enzyme active site was simulated by an assembly of the amino a