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Anion inhibition studies of a β-carbonic anhydrase from Clostridium perfringens

✍ Scribed by Vullo, Daniela; Sai Kumar, R. Siva; Scozzafava, Andrea; Capasso, Clemente; Ferry, James G.; Supuran, Claudiu T.


Book ID
122209130
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
607 KB
Volume
23
Category
Article
ISSN
0960-894X

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An inibition study of the β-carbonic anhydrase (CA, EC 4.2.1.1) DmBCA from the insect Drosophila melanogaster with sulfonamides and sulfamates is reported. Among the panel of 40 investigated compounds, the best DmBCA inhibitors were the sulfonylated benzenesulfonamides and ethoxzolamide, which showe