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Animal models of Type 1 diabetes are relevant to human IDDM — use caution

✍ Scribed by Rabinovitch, Alex


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
20 KB
Volume
14
Category
Article
ISSN
0742-4221

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The study of the immunopathogenesis of IDDM in patients is hampered by several restrictions: 1. The onset of IDDM is relatively late in the natural history of the immune process since almost 80-90% of islets have to be destroyed before insulin deficiency is diagnosed. 2. The site of the immune pro