## Abstract Animal models are important tools in experimental medical science to better understand pathogenesis of human diseases. Once developed, these models can be exploited to test therapeutic approaches for treating functional disturbances observed in the disease of interest. On the basis of e
Animal models of Parkinson’s disease progression
✍ Scribed by Gloria E. Meredith; Patricia K. Sonsalla; Marie-Francoise Chesselet
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 295 KB
- Volume
- 115
- Category
- Article
- ISSN
- 0001-6322
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract ## Background: Parkinson's disease is a progressive neurodegenerative disorder mainly characterized by the loss of dopaminergic neurons from the substantia nigra pars compacta and the presence, in the affected brain regions, of protein inclusions named Lewy Bodies. Despite the fact tha
## Abstract Parkinson's disease is a neurodegenerative disorder whose cardinal manifestations are due primarily to a profound deficit in brain dopamine. Since the 1980s, several therapeutic strategies have been discovered to treat the symptoms of this neurological disorder, but as of yet, none halt
## Abstract Parkinson's disease (PD) is a heterogenous disease likely to be caused by more than one specific aetiological factor. In rare familial cases of PD with similar clinical features to the idiopathic form of the disease, the underlying genetic cause has been identified. These PD‐associated