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Animal models of multiple sclerosis—Potentials and limitations

✍ Scribed by Eilhard Mix; Hans Meyer-Rienecker; Hans-Peter Hartung; Uwe K. Zettl

Book ID: 116840155
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 817 KB
Volume: 92
Category: Article
ISSN: 0301-0082
DOI: 10.1016/j.pneurobio.2010.06.005

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Experimental autoimmune encephalomyelitis (EAE) is a spectrum of neurological disorders in laboratory animals that is used to model multiple sclerosis (MS). However, few agents have translated from efficacy in EAE to the treatment of human disease. Although this may reflect species differences in pa