Animal models for spinal research
β Scribed by Hans-Joachim Wilke
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 63 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0940-6719
No coin nor oath required. For personal study only.
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## Abstract Proximal spinal muscular atrophy, the most frequent genetic cause of childhood lethality, is caused by homozygous loss or mutation of the __SMN1__ gene on human chromosome 5, which codes for the survival motor neuron (SMN) protein. SMN plays a role in the assembly of small nuclear ribon
Animal models of depression are often thought to be of little relevance for understanding the clinical disorder, since the behaviours involved frequently carry little conviction as analogues of human behaviour. However, to dismiss animal models on these grounds is to misunderstand their purpose-or r