Animal models for discovery and assessment of genetic determinants of osteoporosis
β Scribed by RobertJ. Shmookler Reis; RobertH. Ebert II
- Publisher
- Springer-Verlag
- Year
- 2003
- Tongue
- English
- Weight
- 257 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0937-941X
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Osteoporosis and fragility fractures have evolved into major public health issues, particularly given the change in population demographics and the accompanying demand for better preventive as well as treatment options to avert the risk for fracture and its consequences. With the widespread availabi
The use of animal models is a very powerful tool for the preclinical assessment of potential therapies for osteoporosis. However, the effective use of animal models has two prerequisites. The first is the use of appropriate techniques to assess the overall effects of therapy on bone. As spontaneous