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Animal model: Ceroidosis (ceroid-lipofuscinosis) in Australian Cattle dogs

✍ Scribed by Wood, Philip A. ;Sisk, Dudley B. ;Styer, Eloise ;Baker, Henry J. ;Prieur, David J.

Book ID: 102701855
Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 679 KB
Volume: 26
Category: Article
ISSN: 0148-7299
DOI: 10.1002/ajmg.1320260417

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## Abstract The neuronal ceroidlipofuscinoses (NCL) are a group of neurodegenerative disorders and are the most common lysosomal storage diseases of infancy and childhood. Juvenile NCL is caused by __CLN3__ mutation, producing retinal degeneration, uncontrollable seizures, cognitive and motor decli