Primary cutaneous B-cell lymphomas (CBCLs) represent a rare, but distinct group of B-cell neoplasms with a different clinical behaviour to B-cell lymphomas secondarily involving the skin. Fas-Fas ligand (Fasl) expression was investigated in a group of primary and secondary CBCLs to gain an insight i
Angiotropic lymphoma: proliferation of B cells in the capillaries of cutaneous angiomas
β Scribed by T. Kobayashi; S. Munakata; H. Sugiura; M. Koizumi; M. Sumida; K. Murata; H. Shinkai
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 338 KB
- Volume
- 143
- Category
- Article
- ISSN
- 0007-0963
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β¦ Synopsis
We report a 52-year-old patient with cutaneous angiomas on the trunk in association with angiotropic lymphoma involving the nervous system. The lesional skin showed proliferation of atypical B cells in the capillaries. The diagnosis of angiotropic lymphoma with neurological deficits is often difficult before death. Thus, skin biopsy in this case proved to be diagnostic of the central nervous system disease without the risk of brain biopsy. The diagnosis of angiotropic lymphoma in the future may be achievable by biopsy of coincidental angiomas.
π SIMILAR VOLUMES
We report two patients with primary cutaneous B-cell lymphoma who were treated with rituximab, a new anti-CD20 monoclonal antibody. The first patient, who had a diffuse large B-cell lymphoma of the lower leg, achieved an 85% improvement. The second patient, who had a primary cutaneous B-cell lymphom