Angiotension II receptor 1 blocker modifies the expression of apoptosis-related proteins and transforming growth factor-β1 in prostate tissue of spontaneously hypertensive rats

Down-regulation of protein and mRNA expr

Down-regulation of protein and mRNA expression for transforming growth factor-β (TGF-β1) type I and type II receptors in human prostate cancer

✍ Yanping Guo; Stephen C. Jacobs; Natasha Kyprianou 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 French ⚖ 298 KB 👁 1 views

Transforming growth factor-b (TGF-b1) is a potent negative regulator of cell growth that transduces signals through interactions with type I and II receptors. Abnormal expression and mutational alterations of these receptors have been observed in several human malignancies. In this study, we investi