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Angiotensin II accelerates macrophage lipid accumulation via suppression of ATP-binding cassette transporter A1

✍ Scribed by Yasunori Takata; Van Chu; Alan R. Collins; Florian Blaschke; Evren Caglayan; Rajendra K. Tangirala; Willa A. Hsueh

Book ID
116209269
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
63 KB
Volume
18
Category
Article
ISSN
0895-7061

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## Abstract Endothelin‐1 (ET‐1), a potent proatherogenic vasoconstrictive peptide, is known to promote macrophage foam cell formation via mechanisms that are not fully understood. Excessive lipid accumulation in macrophages is a major hallmark during the early stages of atherosclerotic lesions. Cho