Angiotensin converting enzyme inhibitors block mitogenic signalling pathways in rat cardiac fibroblasts

Potential protective role of angiotensin

Potential protective role of angiotensin-converting enzyme inhibitors captopril and enalapril against adriamycin-induced acute cardiac and hepatic toxicity in rats

✍ M. A. Abd El-Aziz; A. I. Othman; M. Amer; M. A. El-Missiry 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 81 KB

## Abstract Captopril and enalapril—angiotensin‐converting enzyme (ACE) inhibitors—were evaluated for their antioxidative protective action against adriamycin‐induced cardiac and hepatic toxicity. Rats were treated with either captopril (10 mg kg^−1^) or enalapril (2 mg kg^−1^) intragastrically (i.