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Angiostatin inhibits experimental liver fibrosis in mice

✍ Scribed by J.Mathys Vogten; TamasA. Drixler; ElisabethA. Velde; MargueriteE. Schipper; TheoJ.M.V. Vroonhoven; EmileE. Voest; InneH.M. Borel Rinkes

Publisher
Springer
Year
2004
Tongue
English
Weight
441 KB
Volume
19
Category
Article
ISSN
0179-1958

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## Abstract ## Background The interaction between fibrogenic cells and extracellular matrix plays a role in liver fibrosis, yet the mechanisms are largely unknown. Secreted protein, acidic and rich in cysteine (SPARC) is a matricellular glycoprotein that is expressed by hepatic stellate cells and