Angiographic follow-up and clinical experience with the flexible tantalum cordis stent

✍ Scribed by Watson, Paul S. ;Ponde, Chandrashekhar K. ;Aroney, Constantine N. ;Cameron, James ;Cannon, Adam ;Dooris, Mark ;Garrahy, Paul J. ;McEniery, Paul T. ;Bett, John H. N.

• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 141 KB
• Volume: 43
• Category: Article
• ISSN: 0098-6569
• DOI: 10.1002/(sici)1097-0304(199802)43:2<168::aid-ccd12>3.0.co;2-k

✦ Synopsis

The Cordis stent is a flexible, highly radioopaque intracoronary stent engineered from a single Tantalum filament folded into a sinusoidal helical coil. It is premounted on a semicompliant balloon expandable stent delivery system. From September 1995-March 1996, 147 Cordis stents were deployed in 105 patients (aged 58 ؎ 12 yr, 71% male). Clinical indications for stenting were unstable angina in 59 (55%), stable angina in 41 (38%), and acute myocardial infarction in 7 (7%). The target vessel was the right coronary artery in 45%, the left anterior descending in 31%, and the circumflex artery in 22%. One stent was deployed in a vein graft, and one stent was deployed in a left internal mammary artery graft. Stent deployment was achieved in all but one patient. Acute in-stent thrombosis occurred in 3 patients (2.9%). Two of these patients required urgent coronary artery bypass surgery. Subacute stent thrombosis occurred in 2 patients (1.9%). Minimum lumen diameter increased from 0.70 ؎ 0.41 mm to 3.50 ؎ 0.60 mm following stent placement. All patients received aspirin. Eighty-one patients (77%) received ticlopidine, and 4 patients (4%) received warfarin therapy. The mean hospital stay was 3.4 ؎ 2.3 days. Six-month follow-up angiography was performed on 50 out of 55 eligible patients at one of the two institutions involved in this study. Computer-assisted quantitative coronary angiography defined a restenosis rate of 26%. Repeat revascularization was required in 8 patients (14.5%) at 6-mo follow-up.

The Tantalum Cordis intracoronary stent is an effective and safe means of treating coronary lesions, even in patients with unstable ischemic syndromes. Acute and subacute rates of in-stent thrombosis were acceptable, and the long-term angiographic restenosis rates and need for repeat revascularization were favorable. Cathet.