Angiogenesis three months after clinical transmyocardial laser revascularization using an excimer laser
✍ Scribed by Jos A.P. van der Sloot; Menno Huikeshoven; Allard C. van der Wal; Raymond Tukkie; Martin J.C. van Gemert; Jan van der Meulen; Johan F. Beek
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 287 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0196-8092
- DOI
- 10.1002/lsm.1130
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Background and Objective
We present for the first time histologic findings 3 months after clinical transmyocardial laser revascularization using a XeCl excimer laser.
Study Design/Materials and Methods
Histology was performed on a patient who died from a noncardiac cause 3 months post‐excimer TMLR.
Results
In the treated myocardium, no patent channels were found but scars were seen with a linear distribution and in continuity with circumscribed small fibrotic endocardial and epicardial scars. The scars were highly vascularized by new vessels, ranging from small capillaries to large thin walled, and sometimes branching ectatic vessels. Sprouting of vessels into the adjacent myocardium was also observed.
Conclusion
These results suggest that angiogenesis might play a role in the clinical improvement after TMLR. Lasers Surg. Med. 29:369–373, 2001. © 2001 Wiley‐Liss, Inc.