Angiogenesis and Direct Myocardial Revascularization
β Scribed by Roger J. Laham MD (auth.), Roger J. Laham MD, Donald S. Baim MD (eds.)
- Publisher
- Humana Press
- Year
- 2005
- Tongue
- English
- Leaves
- 364
- Series
- Contemporary Cardiology
- Edition
- 1
- Category
- Library
No coin nor oath required. For personal study only.
β¦ Synopsis
Despite the rapid progress in surgical and catheter-based revascularization, an alternative treatment strategy is needed for the ever-increasing number of patients who are either not candidates for these therapies or remain symptomatic after revascularization and maximal ongoing medical treatment. In Angiogenesis and Direct Myocardial Revascularization, an interdisciplinary panel of pioneers and opinion leaders review the basic, preclinical, clinical, and developmental pathways to new treatment strategies, such as therapeutic angiogenesis and myogenesis. In their assessments, the authors take advantage of new biological understanding, novel therapeutic targets, multiple available and well-studied therapeutic strategies, and the necessary imaging techniques to measure outcomes. Their in-depth discussions cover the identification of new therapeutic targets and pathways, the investigation of transcriptional factors, master switch molecules, cell-based approaches, chemokines, a better understanding of the effects of aging, endothelial dysfunction, and hypercholesterolemia in response to angiogenic stimuli. Highlights include examination of drug delivery problems, outcomes measure, stem therapy, high-risk interventions, development pathways, and future possibilities.
Authoritative and state-of-the-art, Angiogenesis and Direct Myocardial Revascularization provides all internists, cardiologists, vascular disease specialists, scientists, and industry with a highly effective scientific and clinical basis for helping patients with end-stage ischemic heart disease, peripheral vascular disease, and congestive heart failure.
β¦ Table of Contents
Front Matter....Pages i-xi
No-Option Patients....Pages 1-17
Transcriptional Regulation of Angiogenesis....Pages 19-36
Preclinical Models and Experience to Date....Pages 37-64
The Coronary Microcirculation and Angiogenesis....Pages 65-105
Local and Regional Vascular Delivery Strategies for Therapeutic Angiogenesis and Myogenesis....Pages 107-141
Imaging Angiogenesis....Pages 143-184
Myocardial Angiogenesis....Pages 185-214
Gene Therapy for Angiogenesis in the Treatment of Cardiovascular and Peripheral Arterial Disease....Pages 215-244
Therapeutic Angiogenesis in Peripheral Arterial Disease....Pages 245-259
Bone Marrow Cell Transplantation for Myocardial Regeneration and Therapeutic Angiogenesis....Pages 261-281
Transplantation of Embryonic Stem Cells for Myocardial Regeneration and Angiogenesis....Pages 283-310
Skeletal Myoblast Transplantation for Cardiac Repair....Pages 311-328
Transmyocardial Laser Revascularization....Pages 329-348
Back Matter....Pages 349-357
β¦ Subjects
Cardiology
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