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Angelman Syndrome in Three Siblings: Genetic Model of Epilepsy Associated with Chromosomal DNA Deletion of the GABAA Receptor

✍ Scribed by Tateo Sugimoto; Atsushi Araki; Akihiro Yasuhara; Man Woo; Naoki Nishida; Teruko Sasaki


Book ID
118709114
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
196 KB
Volume
48
Category
Article
ISSN
1323-1316

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## Abstract A substantial body of literature suggests that γ‐aminobutyric acid (GABA) may be involved in the neurochemical pathways contributing to alcohol use and related disorders. Chromosome 5 contains a cluster of GABA~A~ receptor genes, __GABRA1__, __GABRA6__, __GABRB2__, and __GABRG2__, which