Aneuploidy and copy number breakpoints in the genome of lager yeasts mapped by microarray hybridisation

Comprehensive analysis of loss of hetero

Comprehensive analysis of loss of heterozygosity events in glioblastoma using the 100K SNP mapping arrays and comparison with copy number abnormalities defined by BAC array comparative genomic hybridization

✍ Ken C. Lo; Dione Bailey; Tania Burkhardt; Paul Gardina; Yaron Turpaz; John K. Co 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 609 KB

## Abstract We have undertaken an extensive high‐resolution analysis of loss of heterozygosity (LOH) in 30 high grade gliomas using the Affymetrix 100K SNP mapping array. Only 70% of LOH events were accompanied by a copy number loss (CNA~loss~), and of the other 30%, the distal region of 17p prefer