Aneuploidy and cancer
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Ya-Hui Chi; Kuan-Teh Jeang
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Article
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2007
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John Wiley and Sons
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English
β 197 KB
## Abstract The cell's euploid status is influenced by, amongst other mechanisms, an intact spindle assembly checkpoint (SAC), an accurate centrosome cycle, and proper cytokinesis. Studies in mammalian cells suggest that dysregulated SAC function, centrosome cycle, and cytokinesis can all contribut