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Androgens down-regulate the expression of the human homologue of Paternally expressed gene-3 in the prostatic adenocarcinoma cell line LNCaP

✍ Scribed by William Ulrix; Johannes V Swinnen; Walter Heyns; Guido Verhoeven


Book ID
117464244
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
250 KB
Volume
155
Category
Article
ISSN
0303-7207

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BACKGROUND. Matrix metalloproteinases (MMPs) are regulated both positively and negatively at the transcriptional level by a variety of growth factors, oncogenes, and tumor promoters. Induction of the MMP, matrilysin, by epidermal growth factor (EGF) was investigated in a human prostate cancer cell l