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Androgenic correlates of genetic variation in the gene encoding 5α-reductase type 1

✍ Scribed by Justine A. Ellis; Sianna Panagiotopoulos; Aysel Akdeniz; George Jerums; Stephen B. Harrap


Book ID
106251925
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
207 KB
Volume
50
Category
Article
ISSN
1435-232X

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## Abstract Previous __in vitro__ studies demonstrated that bioactive androgen 5α‐dihydrotestosterone (DHT) exerted antiproliferative effects through an interaction with androgen receptor (AR) in breast carcinoma cells. However, AR status has not been examined in association with DHT concentration