## Abstract The androgen receptor signaling axis plays an essential role in the development, function and homeostasis of male urogenital structures including the prostate gland although the mechanism by which the AR axis contributes to the initiation, progression and metastatic spread of prostate c
Androgen receptors in the cytosolic fraction of malignant prostatic tumors and their clinical significance
β Scribed by N. E. Kushlinskii; L. M. Gorilovskii; V. D. Ermilova; N. L. Svetozarskii; B. V. Bukharkin; V. G. Degtyar'
- Publisher
- Springer US
- Year
- 1996
- Tongue
- English
- Weight
- 413 KB
- Volume
- 122
- Category
- Article
- ISSN
- 0007-4888
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## Background: The prognostic significance of primary tumor dna-ploidy and s-phase fraction (spf) was evaluated in patients treated with androgen ablation for regionally localized node-positive prostate cancer. ## Methods: All patients were diagnosed with lymph node involvement by pelvic lymphade
## Abstract Significant but low concentrations (mean 8 fmol/mg cyβtosol protein) of cytosol estrogen receptors were found in 57% of nonβdiseased ovarian tissues, and higher concentrations (mean 211) of cytosol progestin receptors in all these tissues. An approximately similar distribution was found