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Androgen receptor regulation by physiological concentration of the isoflavonoid genistein in LNCaP prostate cancer cells is mediated by estrogen receptor β

✍ Scribed by Jasmin Bektic; Andreas P Berger; Karina Pfeil; Gabriele Dobler; Georg Bartsch; Helmut Klocker


Book ID
118645077
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
69 KB
Volume
2
Category
Article
ISSN
1569-9056

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## Abstract Activation of PKCδ in androgen‐dependent LNCaP prostate cancer cells leads to apoptosis via the activation of p38 MAPK and JNK cascades. We have recently shown that treatment of LNCaP cells with phorbol 12‐myristate 13‐acetate (PMA) leads to a PKCδ‐mediated autocrine release of death fa