Androgen receptor CAG polymorphism and prostate cancer risk
✍ Scribed by Nina Mononen; Tarja Ikonen; Ville Autio; Annika Rökman; Mika P. Matikainen; Teuvo L. Tammela; Olli-P. Kallioniemi; Pasi A. Koivisto; Johanna Schleutker
- Publisher
- Springer
- Year
- 2002
- Tongue
- English
- Weight
- 62 KB
- Volume
- 111
- Category
- Article
- ISSN
- 0340-6717
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## Abstract The androgen receptor (__AR__) gene is a transcription factor responsible for mediating the physiological effects of androgens. Evidence suggests that androgens and the androgen receptor are involved in uterine cell proliferation. A polymorphic CAG repeat in exon 1 of the __AR__ gene en
Several reports have suggested that one or both of the trinucleotide repeat polymorphisms in the human androgen receptor (hAR) gene, (CAG) n coding for polyglutamine and (GGC) n coding for polyglycine, may be associated with prostate cancer risk; but no study has investigated their association with