𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Ancient Phylogenetic Beginnings of Immunoglobulin Hypermutation

✍ Scribed by Jaroslav Kubrycht; Karel Sigler; Michal Růžička; Pavel Souček; Jiří Borecký; Petr Ježek

Book ID
105933035
Publisher
Springer
Year
2006
Tongue
English
Weight
221 KB
Volume
63
Category
Article
ISSN
0022-2844

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

By-products of immunoglobulin somatic hy
By-products of immunoglobulin somatic hypermutation
✍ Mats Bemark; Michael S. Neuberger 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 335 KB

## Abstract The antigen receptor loci are the only loci in humans to undergo programmed somatic gene modification. Although aberrant V(D)J integration and class switch recombination can both give rise to chromosomal translocations, a role for somatic hypermutation in such genomic rearrangements has

Analysis of hypermutation in immunoglobu
Analysis of hypermutation in immunoglobulin heavy chain passenger transgenes
✍ J. Martin Johnston; Sudhakar R. Ihyer; Robin S. Smith; Kuei-Fang Tai; Tara Farme 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 484 KB

## Abstract Somatic hypermutation of immunoglobulin (Ig) genes plays a critical role in the maturation of the human antibody response. The molecular basis of this important process is, however, unknown. To identify __cis__‐acting sequences that initiate and target hypermutation, we have made three