Objective:
To identify anatomical factors associated with major adverse limb events (male) after angioplasty as the basis for a novel morphology-driven classification of infrapopliteal lesions.
Design:
Retrospective-multicenter study.
Materials and methods:
Between march 2004 and october 2010, 1057 limbs from 884 patients with cli due to isolated infrapopliteal lesions were studied. freedom-from male, defined as major amputation or any reintervention, was assessed out to 2 years by the kaplan-meier methods. anatomical predictors and risk stratification for male were analyzed by multivariate analysis.
Results:
Freedom-from male was 47 ยฑ 1% at 2 years. lesion calcification, target vessel diameter<3.0 mm, lesion length>300 mm and no below-the-ankle (ba) run-off were positively associated with male by multivariate-analysis. the total number of risk factors was used to calculate the risk score for each limbs for subsequent categorization into 3 groups with 0 or 1 (low-risk), 2 (moderate-risk) and 3 or 4 (high-risk) factors. freedom-from male at 2 year-rates was 59% in low-risk, 46% in moderate-risk, and 29% in high-risk, respectively.
Conclusion:
Target vessel diameter <3.0 mm, lesion calcification, lesion length > 300 mm and no-ba run-off were associated with male after infrapopliteal angioplasty. risk stratification based on these predictors allows estimation of future incidence of male in cli with isolated infrapopliteal lesions.