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Anatomical-Physiological Approaches in Pharmacokinetics and Pharmacodynamics

✍ Scribed by Professor Laurence E. Mather

Book ID
119926374
Publisher
Springer International Publishing AG
Year
2001
Tongue
English
Weight
788 KB
Volume
40
Category
Article
ISSN
0312-5963

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Physiological pharmacokinetics and pharmacodynamics of (Β±)-verapamil in female rats
✍ Elizabeth L. Todd; Darrell R. Abernethy πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 657 KB

Tissue distribution and pharmacodynamics of verapamil were evaluated during steady state intravenous (i.v.) infusion and after single dose intraperitoneal (i.p.) drug administration to female Sprague-Dawley rats. In one group of rats, verapamil was infused to a steady state concentration at which ti