## Abstract ## BACKGROUND The Pre‐Operative “Arimidex” Compared to Tamoxifen (PROACT) study was a randomized, multicenter study comparing anastrozole with tamoxifen as a preoperative treatment of postmenopausal women with large, operable (T2/3, N0‐2, M0), or potentially operable (T4b, N0‐2, M0) br
✦ LIBER ✦
Anastrozole (‘Arimidex’) blocks oestrogen synthesis both peripherally and within the breast in postmenopausal women with large operable breast cancer
✍ Scribed by Miller, W R; Stuart, M; Sahmoud, T; Dixon, J M
- Book ID
- 109997389
- Publisher
- Nature Publishing Group
- Year
- 2002
- Tongue
- English
- Weight
- 121 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0007-0920
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## Abstract ## BACKGROUND The first analysis of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial (median follow‐up, 33 months) demonstrated that in adjuvant endocrine therapy for postmenopausal patients with early‐stage breast cancer, anastrozole was superior to tamoxifen in terms of d